Home 5 Projects 5 On Going 5 PAS GRAS – De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents, and young adults (Duration: 2023–2028)

PAS GRAS – De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents, and young adults (Duration: 2023–2028)

Duration: 04/2023 – 03/2028

Abstract: PAS GRAS aims to prevent and reverse obesity and associated metabolic complications in four age groups: pre-pubertal children (3-9 yr), adolescents (10-18 yr), young adults (19-25 yr), and adults (25-55). PAS GRAS focuses on four main pillars. 1) Develop a personalized risk assessment tool (RAT): an algorithm that will anticipate obesity priming and development in the critical age groups, and identify risk factors for specific complications in subsequent years that will constitute new outcomes for interventional studies. 2) Develop and implement RAT-based personalized interventions by integrating non-pharmacological lifestyle modifications including Mediterranean Diet components alone or with rational pharmacological targeting metabolic and neuroendocrine mechanisms. 3) Inform and engage effectively target groups on obesity causes, risks and intervention by co-production of creative and interactive digital tools (including a simpler version of the RAT) and personalized diet and physical activity programs. 4) Expand and consolidate the PAS GRAS tailor-made campaign across Europe through developing joint programs for health and food/nutrition literacy and physical activity, with healthcare centres, schools, sports clubs, municipalities, and other relevant actors and public authorities.

Coordinator: Paulo Oliveira, Universidade de Coimbra

Participants (CIAS): Cristina Padez, Daniela Rodrigues, Aristides M. Machado-Rodrigues, Helena Nogueira

Partner institutions:

  • Universidade De Coimbra  (997826391) – COORDINATOR
  • Universita Degli Studi Di Bari Aldo Moro – UNIBA (999840596) – BENEFICIARY
  • Uppsala Universitet – UU (999985029) – BENEFICIARY
  • Universidade Nova De Lisboa – UNL (960782479) – BENEFICIARY
  • Fundacio Eurecat – EURECAT (928030235) – BENEFICIARY
  • Consiglio Nazionale Delle Ricerche – CNR (999979500) – BENEFICIARY
  • Instituto Politecnico De Viana De Castelo – IPVC (998454563) – BENEFICIARY
  • Technische Universitaet Muenchen – TUM (999977463) – BENEFICIARY
  • Instytut Biologii Doswiadczalnej Im. M. Nenckiego Polskiej Akademii Nauk – NENCKI (999489359) – BENEFICIARY
  • Instituto Pedro Nunes Associacao Para A Inovacao E Desenvolvimento Em Ciencia E Tecnologia – IPN (999578502) – BENEFICIARY
  • The European Society For Clinical Investigation – (896926603) – BENEFICIARY
  • Mediagnost Gesellschaft Fur Forschung Und Herstellung Von Diagnostika Gmbh – MEDIAGNOST (955514312) – BENEFICIARY
  • Martin-Luther-Universitat Halle-Wittenberg – MLU (999871539) – BENEFICIARY
  • Associacao Protectora Dos Diabeticos De Portugal – APDP (928326570) – BENEFICIARY
  • AGDCENTRO Associacao De Ginastica Do Centro – (887885912) – BENEFICIARY

Financial support: European Commission, HORIZON Programme – 9.500.000€

Reference: 101080329