Genetics of venous thrombosis (VT) risk in Portuguese patients (Duration: 2016-2018)

by CIAS Gestão | Feb 23, 2016 | Projects

Duration: 2016-2018 Abstract: Several well established or candidate susceptibility loci associated with VT will be analysed by a case/control genetic design in VT patients versus a similar number of controls aimed at identifying subgroups of high-risk genotypes....

Study of polymorphic variations associated with fetal hemoglobin levels (Duration: 2014-2020)

by CIAS Gestão | Dec 23, 2014 | Projects

Duration: 2014-2020 Abstract: To evaluate the association of genetic variants at the HBG2, BCL11A, HMIP or other loci with HbF levels in beta-thalassemia carriers and in normal individuals of Portuguese origin. Coordinator: Licínio Manco (CIAS)...

Genetic variants associated with obesity in Portuguese young adults (Duration: 2014-2018)

by CIAS Gestão | Feb 26, 2014 | Projects

Duration: 2014-2018 Abstract: Several studies emerged associating single nucleotide polymorphisms (SNPs) in common obesity in about 50 loci across the human genome, most of them in adults. Nevertheless, candidate and replication studies of obesity loci among...

Genetics of red cell enzyme deficiencies: mutation profile and selective or demographic influencing factors (Duration: 2010-2018)

by CIAS Gestão | Dec 30, 2010 | Projects

Duration: 2010-2018 Abstract: The main objectives of this project are: 1) to identify mutations in genes such as G6PD, PK, TPI, P5N, HK or GPI leading to red cell enzyme deficiencies in Portuguese patients; and 2) to understand signatures of selective (malaria)...

Study of genetic variants associated with obesity in Portuguese children (Duration: 2010-2015)

by CIAS Gestão | Dec 29, 2010 | Projects

Duration: 2010-2015 Abstract: The main goal of this project is to analyse candidate genetic variants in a sample of Portuguese children, in order to identify genetic variability that could explain the obese phenotype. Coordinator: David Albuquerque...