Physical activity does not impact the FTO genetic variation on the risk of obesity

Obesity is a major public health concern that has experienced an increase in the pediatric and adult population worldwide. While, the literature has focused on the influence of energy‐dense food combined with physical inactivity has a major factor associated with the high prevalence rates, it is also clear that some individuals are more susceptible to the “obesogenic” environments than others.

The latest article published by CIAS’ members (Licínio Manco, Simão Pinho, David Albuquerque, Aristides M. Machado-Rodrigues, and Cristina Padez) shows an association between FTO rs9939609 and obesity or body fat indices in girls but not in boys. Moreover, physical activity was not found to mediate the impact of FTO genetic variation on risk of obesity. Nevertheless, future studies are required to establish systematically whether higher PA levels and different portions of intensity may diminish the FTO‐mediated predisposition to weight gain in children.

The results found were highlighted on some national newspapers. See HERE and HERE.

The complete article, published in the latest volume of the American Journal of Human Biology, can be read HERE.

Physical activity does not impact the FTO genetic variation on the risk of obesity

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